{"_id":"agxzfmlsbGlzdHNpdGVyGAsSC05ld19Db21wYW55GICA4PD19YwLDA","lastupdate":"2024-02-06T00:00:00.000Z","update_date":"2024-02-06T00:00:00.000Z","lastModified":"Oct 21, 2025","active":1,"confidence_score":100,"confidence_score_reason":"markets","urlname":"minovia-therapeutics","minimal_profile":null,"status":"Public","fullstatus":"Public on NASDAQ on Jun, 2025;","acquired":0,"hide_reason":null,"hide_reason_data":null,"hide_reasons":[{"id":"8257rxn4P8EFQOmS5hAAauHyYMhhxrA5u6yWX4XUShpybX3AMNo3Y9","reason":"Pending approval - External entity"},{"id":"aOIaOiiqfpA8UMw6VCTh8ueRmkG3lzDy1NGqEOaJbe11OrCzMTCCd6","reason":"The company is a service provider"},{"id":"ddgjKuc3GgH8E5UehSVJviRl471BCajL1plO8HtGoOojy2NivYqQ7x","reason":"Owner asked to delete"},{"id":"EjOKM211H1ira9J63oaGPuUxvr7Oba55TZo3NWsFO5uhbNu7o4x4zD","reason":"The company is not Israeli"},{"id":"J7fQJtnT3GdWWSE3MD8rzaW65LJ4jEIKxSZnneQiReONdZjG3zIqWe","reason":"Owner asked to hide in the meantime"},{"id":"NxlAC3ReFb5ksiYNLp2FnUyluoJzwRCYfcF7xpTZaPM53SdWQ5kv0B","reason":"Pending approval"},{"id":"RhC1tlwXzioK0MfzBII3H2wepEfQOfKVktmdwqeqTJjGi3ZaBWUqZo","reason":"The company is not innovative"},{"id":"S0Ed46vNI6vZYVxLedANWGjas23K6hY0QdsCtiGYL7lshqIEdLV3sA","reason":"The company ceased operations in Israel"},{"id":"VTANq7bEvlsEcPjp0ghelXfShaCosgndONGjgU730aAOxXtaDIF5j3","reason":"This is a product of an existing company"}],"type":"Startup","logokey":"$oMjYEagIne9f6gCE6HhBSTPCt5kHNArWUHh7bCtwG5cxteXYeiITxi.png","name":"Minovia Therapeutics","oneliner":"Mitochondrial Augmentation Cell-therapy Platform","registrar":"514704485","website":"https://minoviatx.com","careerspage":"https://minoviatx.com/careers","founded_month":12,"founded_year":2011,"formernames":[],"sociallinks":{"twitter":"https://twitter.com/minoviatx","youtube":"https://www.youtube.com/channel/UCL3q1kF6qdinl3xb0Eos9VA","facebook":"","linkedin":"https://www.linkedin.com/company/40691057","instagram":""},"social":["https://www.youtube.com/channel/UCL3q1kF6qdinl3xb0Eos9VA","https://www.linkedin.com/company/40691057","https://twitter.com/minoviatx"],"flattenedsociallinks":"https://www.youtube.com/channel/UCL3q1kF6qdinl3xb0Eos9VA|https://www.linkedin.com/company/40691057|https://twitter.com/minoviatx","apps":{"appstore":"","googleplay":""},"is_claimed_by_owner":null,"employees":"11-50","employees_exact":26,"patent":1,"raised":28350000,"stage":"Public","public_stage":"Public","primary_sector_key":"agxzfmlsbGlzdHNpdGVyJAsSF0Jhc2VDbGFzc2lmaWNhdGlvbk1vZGVsGICA4LuwgtgKDA","primary_sector":"Health Tech & Life Sciences","alternativenames":["Minovia"],"about":"Minovia Therapeutics treats mitochondrial diseases through cell therapy using its Mitochondrial Augmentation Therapy (MAT) platform. 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This clearance allows Minovia to initiate a Phase II clinical trial for pediatric patients with Pearson Syndrome, a severe mitochondrial disease. The trial aims to evaluate the safety and efficacy of MNV-201, focusing on improving growth and quality of life. The FDAs clearance marks a significant milestone for Minovia, enabling them to advance their allogeneic mitochondrial therapy approach. 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The therapy involves enriching hematopoietic stem cells with healthy mitochondria and injecting them back into patients. The company has conducted successful trials on children with Pearson syndrome, a bone marrow disorder. The children showed improvement in aerobic function, weight gain, and strength. Minovia is now developing an off-the-shelf product using mitochondria from donated placentas. The first indication for the product is still Pearson syndrome, but the company plans to expand to other indications. Minovia intends to collaborate with big pharma companies and has already partnered with Astellas Pharma. The company has received investments totaling nearly $30 million and holds 70 patents. 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The partnership aims to accelerate the creation of allogeneic mitochondrial cell therapy programs, with the two companies jointly researching cell therapy program candidates. Under the terms of the agreement, Minovia will receive an upfront cash payment of $20M USD from Astellas. If Astellas develops and commercializes product candidates for diseases caused by mitochondrial dysfunction, Minovia could receive up to $420M USD per product in future development, regulatory and commercial milestone payments from Astellas.","partners":"Astellas Pharma Inc.","customers":"Not mentioned","investors":"Astellas Pharma Inc.","confidence":9,"key_topics":["Strategic Collaboration","License Agreement","Cell Therapy","Mitochondrial Dysfunction","Investment"],"date_of_event":"Not mentioned","valuation_amount":"Not mentioned","impact_on_company":"growth-positive","investment_amount":"$20M USD upfront, up to $420M USD in future milestone payments","structured_issues":["Partners","Investment"],"acquisition_amount":"Not mentioned","structuredIssuesShow":"#Partners  #Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"L548ZEyHgTRGXr2H2uK6KWU9nxRNpMjAc470EELi40RzIVNT1bV4yj","news_summary":"Astellas and Minovia Therapeutics Announce Strategic Collaboration for Novel Mitochondrial Cell Therapy Programs","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"bce6deaf-3504-4e21-be8d-7c8f6727b433","date":"Mar 12, 2021","link":"https://www.fiercebiotech.com/biotech/mitochondrial-biotech-minovia-therapeutics-nabs-biopharma-veteran-alan-jacobs-as-new-chief","source":"www.fiercebiotech.com","visible":1,"analysis":{"tags":"Legal","company":"Questex LLC","layoffs":"N/A","summary":"The article discusses the terms of use and privacy policy of Questex LLC.","partners":"N/A","customers":"N/A","investors":"N/A","confidence":8,"key_topics":["Questex LLC","Terms of use","Privacy Policy"],"date_of_event":"N/A","valuation_amount":"N/A","impact_on_company":"N/A","investment_amount":"N/A","structured_issues":[],"acquisition_amount":"N/A","entityGrowthIconPath":"none;"},"sentiment":"N/A","analysisId":"ziKTw2rhpxF0Pltn1NHGwCpe5sRLdHqUrSOOwhxxAoMntLK49HfoqV","news_summary":"Mitochondrial biotech Minovia Therapeutics nabs biopharma veteran Jacobs as new chief medical officer","analysisStructuredIssuesDisplay":"none","analysisImpactOnCompanyDisplay":"block"},{"id":"9f2d6f7f-ec65-4154-82d6-c704bda883e8","date":"Nov 23, 2020","link":"https://www.businesswire.com/news/home/20201123005571/en/Minovia-Therapeutics-Announces-Manufacturing-Partnership-with-BioSpherix-and-Appoints-David-O%E2%80%99Donnell-as-Global-Head-of-Manufacturing-and-Supply-Chain","source":"www.businesswire.com","visible":1,"analysis":{"entityGrowthIconPath":"none;"},"sentiment":null,"analysisId":"zlR26aiKxexfnO1Ga8pSmaR5Sz5Ok0FnlMymaQUEAPein2u1x2DFJV","news_summary":"Minovia Therapeutics Announces Manufacturing Partnership with BioSpherix and Appoints David O'Donnell as Global Head of Manufacturing and Supply Chain","analysisStructuredIssuesDisplay":"none","analysisImpactOnCompanyDisplay":"block"},{"id":"6f2cb89b-a6d1-4361-aa93-693e9444ee9b","date":"Nov 9, 2020","link":"https://www.businesswire.com/news/home/20201109005274/en/Minovia-Therapeutics-to-Participate-at-Upcoming-Credit-Suisse-Healthcare-Conference-on-November-12th","source":"www.businesswire.com","visible":1,"analysis":{"entityGrowthIconPath":"none;"},"sentiment":null,"analysisId":"FNLWHGErW9QdzKuvdwWZHXwBM2Eghw9kemBU8glBruL25n8RYemZKs","news_summary":"Minovia Therapeutics to Participate at Upcoming Credit Suisse Healthcare Conference on November 12th","analysisStructuredIssuesDisplay":"none","analysisImpactOnCompanyDisplay":"block"},{"id":"3812467e-7ea1-469a-95e5-0b0eaed5b772","date":"Jun 15, 2020","link":"https://bostonrealestatetimes.com/minovia-therapeutics-leases-4600-sf-in-woburn/","source":"bostonrealestatetimes.com","visible":1,"analysis":{"tags":"expansion","company":"Minovia Therapeutics","layoffs":null,"summary":"Minovia Therapeutics, an international life sciences firm, is expanding its U.S. operations by opening a 4,600-square-foot facility in Woburns technology cluster. The company, which specializes in developing cell therapy for rare mitochondrial diseases, will commence its GMP manufacturing at the new facility. The location and buildout of the space are ideal for Minovias operations. The expansion signifies growth for the company.","partners":null,"customers":null,"investors":null,"confidence":8,"key_topics":["expansion","cell therapy","rare mitochondrial diseases","GMP manufacturing","new facility"],"date_of_event":null,"valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Expand"],"acquisition_amount":null,"structuredIssuesShow":"#Expand","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"ysoVEAeH7oCO9z1fPNAyaDW5HTDNE82M5TuFdeKycdyRuD18KsiWQL","news_summary":"Minovia Therapeutics Leases 4,600 SF in Woburn - Boston Real Estate Times","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"217cdc88-0ec0-4e79-89a0-70276a74489a","date":"Jul 16, 2019","link":"https://www.biospace.com/article/new-hope-for-rare-mitochondrial-diseases-an-interview-with-minovia-therapeutics-natalie-yivgi-ohana/","source":"www.biospace.com","visible":1,"analysis":{"tags":["mitochondrial diseases","clinical trial","cell therapy","rare diseases"],"company":"Minovia Therapeutics","layoffs":null,"summary":"Minovia Therapeutics has dosed the first patient in a Phase I/II clinical trial for Pearson syndrome, a rare mitochondrial disease. The company is using its Mitochondrial Augmentation Therapy (MAT) platform, which aims to increase the level of normal mitochondrial DNA using autologous stem cells enriched with normal mitochondria. The trial will evaluate the safety and clinical effects of the companys autologous CD34+ cells enriched with blood-derived mitochondria in pediatric patients. Minovia is also planning to open an office in Cambridge, Massachusetts and hire 20 employees by the end of 2020. 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