{"_id":"agxzfmlsbGlzdHNpdGVyGAsSC05ld19Db21wYW55GICAgJ6btugJDA","lastupdate":"2023-08-22T00:00:00.000Z","update_date":"2023-08-22T00:00:00.000Z","lastModified":"Sep 21, 2024","active":1,"confidence_score":101,"confidence_score_reason":"markets","urlname":"nucleix","minimal_profile":null,"status":"","fullstatus":"","acquired":0,"hide_reason":null,"hide_reason_data":null,"hide_reasons":[{"id":"8257rxn4P8EFQOmS5hAAauHyYMhhxrA5u6yWX4XUShpybX3AMNo3Y9","reason":"Pending approval - External entity"},{"id":"aOIaOiiqfpA8UMw6VCTh8ueRmkG3lzDy1NGqEOaJbe11OrCzMTCCd6","reason":"The company is a service provider"},{"id":"ddgjKuc3GgH8E5UehSVJviRl471BCajL1plO8HtGoOojy2NivYqQ7x","reason":"Owner asked to delete"},{"id":"EjOKM211H1ira9J63oaGPuUxvr7Oba55TZo3NWsFO5uhbNu7o4x4zD","reason":"The company is not Israeli"},{"id":"J7fQJtnT3GdWWSE3MD8rzaW65LJ4jEIKxSZnneQiReONdZjG3zIqWe","reason":"Owner asked to hide in the meantime"},{"id":"NxlAC3ReFb5ksiYNLp2FnUyluoJzwRCYfcF7xpTZaPM53SdWQ5kv0B","reason":"Pending approval"},{"id":"RhC1tlwXzioK0MfzBII3H2wepEfQOfKVktmdwqeqTJjGi3ZaBWUqZo","reason":"The company is not innovative"},{"id":"S0Ed46vNI6vZYVxLedANWGjas23K6hY0QdsCtiGYL7lshqIEdLV3sA","reason":"The company ceased operations in Israel"},{"id":"VTANq7bEvlsEcPjp0ghelXfShaCosgndONGjgU730aAOxXtaDIF5j3","reason":"This is a product of an existing company"}],"type":"Startup","logokey":"$Ry36eLj6duP7RMtZkQe792U5jfVtKwuWffB5hUPv7cRS51D0fwBGZm","name":"Nucleix","oneliner":"Noninvasive Testing for Early Detection of Cancer","registrar":"514134568","website":"https://nucleix.com","careerspage":"https://nucleix.com/company/","founded_month":5,"founded_year":2008,"formernames":[],"sociallinks":{"twitter":"https://twitter.com/nucleix2","youtube":"https://www.youtube.com/channel/UCZ-2RIVy9QbNCsko6S3L1Kw","facebook":"https://www.facebook.com/Nucleix-100608201471224","linkedin":"https://www.linkedin.com/company/1670969","instagram":""},"social":["https://www.youtube.com/channel/UCZ-2RIVy9QbNCsko6S3L1Kw","https://www.youtube.com/channel/UCFXRV2cV5QZVAv-d_Y-_2BQ","https://www.linkedin.com/company/1670969","https://twitter.com/nucleix2","https://www.facebook.com/Nucleix-100608201471224"],"flattenedsociallinks":"https://www.youtube.com/channel/UCZ-2RIVy9QbNCsko6S3L1Kw|https://www.youtube.com/channel/UCFXRV2cV5QZVAv-d_Y-_2BQ|https://www.linkedin.com/company/1670969|https://twitter.com/nucleix2|https://www.facebook.com/Nucleix-100608201471224","apps":{"appstore":"","googleplay":""},"is_claimed_by_owner":1,"employees":"51-200","employees_exact":69,"patent":1,"raised":88300000,"stage":"C","public_stage":"C","primary_sector_key":"agxzfmlsbGlzdHNpdGVyJAsSF0Jhc2VDbGFzc2lmaWNhdGlvbk1vZGVsGICA4LuwgtgKDA","primary_sector":"Health Tech & Life Sciences","alternativenames":[""],"about":"Nucleix is a liquid biopsy company revolutionizing cancer treatment with earlier disease detection at a time when intervention can bring the greatest impact for patients. Leveraging NGS-based and PCR-based technology to identify methylation changes, the Company’s pioneering testing approach uses methylation-based identification for early-stage and recurring cancer detection. The Company’s non-invasive EpiCheck® delivers highly accurate and sensitive results, all while providing a seamless testing option for physicians, patients, and the healthcare system. The Company is building an EpiCheck® franchise, beginning with the Bladder EpiCheck® kit, CE-marked and available in Europe for primary and recurrent bladder cancer and upper tract urinary cancer, and FDA 510(k) cleared for bladder cancer recurrence in the United States. 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Their Lung EpiCheck blood test analyzes changes in methylation markers to screen for lung cancer in high-risk individuals based on smoking history.","partners":null,"customers":null,"investors":"Sands Capital, RA Capital, Zohar Zisapel, OrbiMed","confidence":9,"key_topics":["Cancer screening tests","Funding","Appointment of chief scientific officer","Advancements in EpiCheck NGS platform","Lung cancer detection program"],"date_of_event":"2022-01-05","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":"$22 million","structured_issues":["Investment","Management Changes"],"acquisition_amount":null,"structuredIssuesShow":"#Investment  #Management Changes","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"EEY8SssjnGX9MATRDfKC80bphWrLPvAmkzFCDvzgmbnoemPPXQW3Xb","news_summary":"Nucleix announces $22 million in funding, advancements in lung cancer detection program","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"e4d457bd-514b-4444-8f18-2dbafa276f5b","date":"Apr 7, 2021","link":"https://en.globes.co.il/en/article-liquid-biopsy-co-nucleix-raises-55m-1001366684","source":"en.globes.co.il","visible":1,"analysis":{"tags":"investment, expand","company":"Nucleix","layoffs":null,"summary":"Nucleix, a liquid biopsy developer for the earlier detection of cancer, has completed a $55 million financing round. 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The financing round was led by RA Capital Management and included participation from new investors BlackRock, Lilly Asia Ventures, LYFE Capital, and MILFAM, as well as existing investors.","partners":null,"customers":null,"investors":"RA Capital Management, BlackRock, Lilly Asia Ventures, LYFE Capital, MILFAM, OrbiMed, Aurum Ventures, DSC Investment, OCI Bio Investments, Zohar Zisapel","confidence":9,"key_topics":["Liquid biopsy","Cancer detection","Financing round","Methylation technology","Lung cancer"],"date_of_event":"April 7, 2021","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":"$55 million","structured_issues":["Investment"],"acquisition_amount":null,"structuredIssuesShow":"#Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"Ng8v2W9JIpwtZtOv23ltxoUWNfNb9YTQ68SltADEsL32Bvje0PiTlI","news_summary":"Liquid biopsy co Nucleix raises $55m","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"7284d61c-461c-4f85-a3f0-ce504508a131","date":"Nov 18, 2020","link":"https://www.businesswire.com/news/home/20201118005421/en/Nucleix%E2%80%99s-BE-Safe-Home-Project-Brings-Bladder-Cancer-Surveillance-to-Patients%E2%80%99-Homes-During-COVID-19-Pandemic-and-Beyond","source":"www.businesswire.com","visible":1,"analysis":{"entityGrowthIconPath":"none;"},"sentiment":null,"analysisId":"syEydb5d3LP3gle89Xyv5Ey0MwdEN7l2paGijlx5AGy5zUpx7JMVVF","news_summary":"Nucleix's BE Safe @Home Project Brings Bladder Cancer Surveillance to Patients' Homes During COVID-19 Pandemic and Beyond","analysisStructuredIssuesDisplay":"none","analysisImpactOnCompanyDisplay":"block"},{"id":"7a2b1ff4-1e1a-4a98-9849-e09b2236f11d","date":"Oct 29, 2020","link":"https://www.biospace.com/article/releases/nucleix-s-lung-epicheck-liquid-biopsy-test-detects-85-percent-of-early-stage-lung-cancers-in-high-risk-smokers-study-published-in-european-respiratory-journal-/","source":"www.biospace.com","visible":1,"analysis":{"entityGrowthIconPath":"none;"},"sentiment":null,"analysisId":"AAVFMteXxRq9PYnb0GfTrN8PxrhoXqsNL1faXCjyaXRcayEK5LluMG","news_summary":"Nucleix's Lung EpiCheck® Liquid Biopsy Test Detects 85% of Early Stage Lung Cancers in High-Risk Smokers, Study Published in European Respiratory Journal  BioSpace","analysisStructuredIssuesDisplay":"none","analysisImpactOnCompanyDisplay":"block"},{"id":"93d121f1-e894-45d4-b2a8-58c383386f49","date":"Sep 24, 2020","link":"https://www.bioworld.com/articles/498172-data-supports-accuracy-and-performance-of-nucleixs-bladder-epicheck-in-nmibc-surveillance?v=preview","source":"www.bioworld.com","visible":1,"analysis":{"tags":"Clinical Cancer Diagnostics","company":"Nucleix Ltd.","layoffs":null,"summary":"An independent analysis of studies of Nucleix Ltd.’s Bladder Epicheck demonstrate high diagnostic accuracy and performance in monitoring for disease recurrence in patients with non-muscle invasive bladder cancer (NMIBC).","partners":null,"customers":null,"investors":null,"confidence":8,"key_topics":["Nucleix Ltd.","Bladder Epicheck","diagnostic accuracy","performance","NMIBC"],"date_of_event":"Sep. 24, 2020","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Customers"],"acquisition_amount":null,"structuredIssuesShow":"#Customers","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"neD1WetM5KQmcmmb5gVrRZCfLTctt1hpt1IF2udfwnP1iogJCt3NiQ","news_summary":"Data supports accuracy and performance of Nucleix's Bladder Epicheck in NMIBC surveillance","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"136d60c8-7b69-410a-96ea-d9c490288fc5","date":"Jun 9, 2020","link":"http://www.digitaljournal.com/pr/4705784","source":"www.digitaljournal.com","visible":1,"analysis":{"tags":"data collection","company":"Flaskdata.io","layoffs":null,"summary":"Flaskdata.io, a SaaS company, is being used by a customer in the detection of early stage lung cancer. The company specializes in helping life sciences companies complete their clinical trials faster. Nucleix Ltd. is one of the successful companies that have used Flaskdata.ios services. Flaskdata.io provides a SaaS platform for clinical trial management and offers various products such as Flask Forms and Flask API. The company aims to further modern life sciences and assist in developing new tests. They collaborate with partners to develop business globally.","partners":null,"customers":["Nucleix Ltd."],"investors":null,"confidence":8,"key_topics":["data collection","clinical trials","cancer detection","SaaS platform","patient engagement"],"date_of_event":null,"valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Customers"],"acquisition_amount":null,"structuredIssuesShow":"#Customers","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"b7L417B40RjYzfhpH2G4eDYQfEVOUZ4c2HengOqOJFsTvnu32jQHDl","news_summary":"Flask Real Time Analytics Help Flaskdata Customer Detect Early Stage Lung Cancer With Blood Test","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"a42a9d28-1ce9-45ed-9f85-55c4a5ac2a87","date":"May 19, 2020","link":"https://www.genomeweb.com/pcr/israels-nucleix-targeting-us-market-noninvasive-bladder-lung-cancer-assays#.XuEVYjpKhPY","source":"www.genomeweb.com","visible":1,"analysis":{"tags":"liquid biopsy","company":"Nucleix","layoffs":null,"summary":"Israeli liquid biopsy startup Nucleix plans to enter the US cancer detection market with diagnostic assays for early-stage cancers. The company aims to launch a lung cancer diagnostic assay next year and is building a CLIA-certified, CAP-accredited lab in the US. Nucleix recently completed a clinical trial for its Bladder EpiCheck cancer diagnostic assay and plans to submit it to the FDA for clearance. The companys EpiCheck technology searches for methylation patterns on circulating tumor DNA in a patients liquid sample. Nucleix is also developing an early-stage lung cancer diagnostic test called Lung EpiCheck. The company has raised $33 million in funding, including investments from Orbimed, Aurum, Zohar Zisapel, DSC, and OCI.","partners":null,"customers":null,"investors":["Orbimed","Aurum","Zohar Zisapel","DSC","OCI"],"confidence":8,"key_topics":["cancer detection","diagnostic assays","liquid biopsy","methylation biomarkers","CLIA-certified lab"],"date_of_event":null,"valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Customers","Investment"],"acquisition_amount":null,"structuredIssuesShow":"#Customers  #Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"kVeTNMqURqgU6wFCIcoNDsZ3TTusUZgBNS8l7KWQfWmAbe9EGFHaoa","news_summary":"Israel's Nucleix Targeting US Market With Noninvasive Bladder, Lung Cancer Assays","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"7bba9e0f-bbfb-4b1b-a0f5-4e2c5f99fc38","date":"Feb 24, 2019","link":"https://www.jpost.com/Jpost-Tech/Business-and-Innovation/New-non-invasive-bladder-cancer-test-transforms-invasive-follow-up-process-581357","source":"www.jpost.com","visible":1,"analysis":{"tags":"bladder cancer","company":"Nucleix","layoffs":null,"summary":"Nucleix, a cancer diagnostic company, has developed the Bladder EpiCheck, a urine test for monitoring bladder cancer. 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The funding comes from the EIC pilot SME Instrument Phase II European program, which is part of Horizon 2020. Nucleix plans to use the funding to accelerate the development of Lung EpiCheck and begin extensive clinical trials in Europe and the US in the beginning of next year.","partners":null,"customers":null,"investors":null,"confidence":9,"key_topics":["Funding","Screening diagnostic blood test","Lung cancer","Horizon 2020","Clinical trials"],"date_of_event":"July 30, 2018","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":"€2.5 million","structured_issues":["Investment"],"acquisition_amount":null,"structuredIssuesShow":"#Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"FuPC7iXKFyNwVqRKg3pQsfRTmdJlQXXYqxBS32Qz760HFJqU4NGEAm","news_summary":"Israeli cancer detection co Nucleix wins €2.5m EU grant","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"a74f046d-efd1-49a4-88b1-3f1f08447443","date":"Jul 24, 2018","link":"https://www.prnewswire.com/news-releases/nucleix-announces-publication-of-non-invasive-bladder-cancer-recurrence-detection-study-showing-best-in-class-performance-300685446.html","source":"www.prnewswire.com","visible":1,"analysis":{"tags":"cancer detection, urine test, bladder cancer recurrence","company":"Nucleix Ltd.","layoffs":null,"summary":"Nucleix Ltd., a cancer detection and screening company, announced the publication of a European study on its Bladder EpiCheck urine test for the detection of bladder cancer recurrence. The study demonstrated the high performance of Bladder EpiCheck and its potential to reduce invasive procedures. The test showed a high negative predictive value (NPV) and sensitivity, making it a valuable tool for clinical decision making. Bladder EpiCheck is a CE approved urine test that has been clinically validated in leading hospitals and labs in Europe. The company is also developing additional assays for the detection of other types of cancers. The market penetration of Bladder EpiCheck looks promising, with several leading hospitals and labs in Europe already using the test.","partners":null,"customers":null,"investors":null,"confidence":8,"key_topics":["Bladder EpiCheck","urine test","bladder cancer recurrence","clinical study","non-invasive detection"],"date_of_event":"July 24, 2018","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Customers"],"acquisition_amount":null,"structuredIssuesShow":"#Customers","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"yRgwd3qRcQUyNGfnD17R0gqJpf7ex1U3c2TsihSx53wYGWLlW7si26","news_summary":"Nucleix Announces Publication of Non-Invasive Bladder Cancer Recurrence Detection Study Showing Best-in-Class Performance","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"6b2dfaeb-6bc2-4e23-83a0-86a19b1b24a4","date":"Mar 14, 2018","link":"https://www.prnewswire.com/news-releases/nucleix-announces-its-bladder-epicheck-availability-on-the-qiagen-rotor-gene-q-platform-300613783.html","source":"www.prnewswire.com","visible":1,"analysis":{"tags":"cancer detection","company":"Nucleix","layoffs":null,"summary":"Nucleix, a cancer detection and screening company, announced the compatibility of its Bladder EpiCheck with the Rotor-Gene Q real-time PCR platform. This widens the available market for Bladder EpiCheck, allowing more laboratories to offer the companys assays. The Rotor-Gene Q platform is widely placed in the target customer segments of pathology and molecular diagnostics. Nucleixs first product, Bladder EpiCheck, is a urine test for monitoring the recurrence of bladder cancer. The companys pipeline includes a screening diagnostic blood test for early lung cancer detection. 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