{"_id":"agxzfmlsbGlzdHNpdGVyGAsSC05ld19Db21wYW55GICAoIPk7Y4LDA","lastupdate":"2023-10-23T00:00:00.000Z","update_date":"2023-10-23T00:00:00.000Z","lastModified":"Sep 21, 2024","active":1,"confidence_score":99,"confidence_score_reason":"markets","urlname":"append-medical","minimal_profile":null,"status":"","fullstatus":"","acquired":0,"hide_reason":null,"hide_reason_data":null,"hide_reasons":[{"id":"8257rxn4P8EFQOmS5hAAauHyYMhhxrA5u6yWX4XUShpybX3AMNo3Y9","reason":"Pending approval - External entity"},{"id":"aOIaOiiqfpA8UMw6VCTh8ueRmkG3lzDy1NGqEOaJbe11OrCzMTCCd6","reason":"The company is a service provider"},{"id":"ddgjKuc3GgH8E5UehSVJviRl471BCajL1plO8HtGoOojy2NivYqQ7x","reason":"Owner asked to delete"},{"id":"EjOKM211H1ira9J63oaGPuUxvr7Oba55TZo3NWsFO5uhbNu7o4x4zD","reason":"The company is not Israeli"},{"id":"J7fQJtnT3GdWWSE3MD8rzaW65LJ4jEIKxSZnneQiReONdZjG3zIqWe","reason":"Owner asked to hide in the meantime"},{"id":"NxlAC3ReFb5ksiYNLp2FnUyluoJzwRCYfcF7xpTZaPM53SdWQ5kv0B","reason":"Pending approval"},{"id":"RhC1tlwXzioK0MfzBII3H2wepEfQOfKVktmdwqeqTJjGi3ZaBWUqZo","reason":"The company is not innovative"},{"id":"S0Ed46vNI6vZYVxLedANWGjas23K6hY0QdsCtiGYL7lshqIEdLV3sA","reason":"The company ceased operations in Israel"},{"id":"VTANq7bEvlsEcPjp0ghelXfShaCosgndONGjgU730aAOxXtaDIF5j3","reason":"This is a product of an existing company"}],"type":"Startup","logokey":"$esyZaIVz7kglweREBrWjC05CKCInZV3nAKyTMsnemBUf15C6TKeaQJ","name":"Append Medical","oneliner":"Trans-septal Left Atrial Appendage Closure Device","registrar":"515554335","website":"https://appendmedical.com","careerspage":"","founded_month":11,"founded_year":2016,"formernames":[],"sociallinks":{"twitter":"https://twitter.com/appendmedical","youtube":"","facebook":"","linkedin":"https://www.linkedin.com/company/30743186","instagram":""},"social":["https://twitter.com/appendmedical","https://www.linkedin.com/company/30743186"],"flattenedsociallinks":"https://twitter.com/appendmedical|https://www.linkedin.com/company/30743186","apps":{"appstore":"","googleplay":""},"is_claimed_by_owner":1,"employees":"11-50","employees_exact":24,"patent":1,"raised":12550000,"stage":"A","public_stage":"A","primary_sector_key":"agxzfmlsbGlzdHNpdGVyJAsSF0Jhc2VDbGFzc2lmaWNhdGlvbk1vZGVsGICA4LuwgtgKDA","primary_sector":"Health Tech & Life Sciences","alternativenames":[""],"about":"Append Medical has developed a minimally invasive implantable device designed to reduce stroke risk in patients suffering from atrial fibrillation.  The Append Medical system is designed to prevent blood clot leakage by achieving complete LAA closure thus reducing the risk of stroke in patients with non-valvular atrial fibrillation. Its unique design may allow it to mitigate device-related thromboembolism risk by leaving minimal foreign material at the closure site.\n\nThe Left Atrial Appendage exclusion technology was invented by Dr. Leonid Sternik and developed at Sheba Medical Center, further licensed by Append Medical. The company is a portfolio company of MEDX Xelerator.","climatetech_description":null,"is_climatetech_relevant":null,"phone":"","country":null,"address":{"israeli":[{"id":"477e2c9e-a416-4354-b389-ebf94a905c9b","city":"Or Yehuda","type":null,"address":"Ariel Sharon Boulevard 8, Or Yehuda, Israel","placeid":null,"notactive":0,"openeddate":null,"registrarid":null,"firstrdcenter":0,"registrarname":null}],"officesabroad":null},"headquarter_address":null,"district":"Center District","news":[{"id":"JlvRs8Std3sZS13fTjPpCcm9y3NlBlrLzcd2ZfSf82Jsu0yUCgOwD9","date":"Jul 6, 2023","link":"https://www.finsmes.com/2023/07/append-medical-raises-4-35m-in-initial-closing-of-extended-series-a.html","source":"www.finsmes.com","visible":1,"analysis":{"tags":"Investment, Medical Technology","company":"Append Medical","layoffs":"Not mentioned","summary":"Append Medical, an Israel-based medical device company, has raised $4.35 million in an extended Series A funding round. The funds will be used to complete the development of and support the First-in-Human Study of the Appligator™, a device designed to prevent stroke in atrial fibrillation patients by closing the left atrial appendage (LAA) without requiring any metal implants. Investors included Shoni Health Ventures and ALIVE Israel HealthTech Fund, along with participants from the first tranche of the A round.","partners":"Not mentioned","customers":"Not mentioned","investors":["Shoni Health Ventures","ALIVE Israel HealthTech Fund"],"confidence":9,"key_topics":["Series A Funding","Medical Device","Stroke Prevention","Investors","Product Development"],"date_of_event":"06/07/2023","valuation_amount":"Not mentioned","impact_on_company":"growth-positive","investment_amount":"$4.35 million","structured_issues":"Investment","acquisition_amount":"Not mentioned","structuredIssuesShow":"#Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"k9tBzrtKuWNTk8s2CzuH5sGm6Zml5asANkXFZp07Am21i43rvKfOQu","news_summary":"Append Medical Raises $4.35M in Initial Closing of Extended Series A","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"7c66222a-e198-4c80-ae6d-91f9ff216977","date":"Aug 4, 2021","link":"https://www.prnewswire.com/news-releases/append-medical-completes-7-4m-million-series-a-round-301348040.html","source":"www.prnewswire.com","visible":1,"analysis":{"tags":"medical technology","company":"Append Medical","layoffs":null,"summary":"Append Medical has completed a $7.4 million Series A financing round, which will enable the company to complete development and perform its first clinical trial. The company has developed a no-implant minimally invasive solution for transcatheter Left Atrial Appendage (LAA) exclusion, aimed at reducing stroke risk in atrial fibrillation patients. The financing round was led by an unnamed strategic company and MedTecX LP, along with other investors. The company was founded in 2017 and is a member of MEDX Xelerator, a med-tech incubator formed as a collaboration between Boston Scientific, Intellectual Ventures, MEDX Ventures, and Sheba Medical Center.","partners":null,"customers":null,"investors":"unnamed strategic company, MedTecX LP, Boston Scientific, MEDX Ventures, Intellectual Ventures","confidence":9,"key_topics":["financing round","no-implant solution","stroke prevention","atrial fibrillation","clinical trial"],"date_of_event":"August 4, 2021","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":"$7.4 million","structured_issues":["Investment"],"acquisition_amount":null,"structuredIssuesShow":"#Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"P6B3s1DjeriVDaH8seH4WbUHy9PhpGhHZuQqtXNyslzOIpJt22HRpZ","news_summary":"Append Medical Completes $7.4M Million Series A Round","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"9eb85618-9240-450f-956c-4e6ffa758f3b","date":"Nov 14, 2020","link":"https://www.jpost.com/health-science/israeli-company-soon-to-begin-trial-on-stroke-risk-reduction-device-649063","source":"www.jpost.com","visible":1,"analysis":{"tags":"medical technology","company":"Append Medical","layoffs":null,"summary":"Israeli medical start-up Append Medical has been given special permission to present their technology to help atrial fibrillation patients. The companys device, called The Appligator, is designed to seal the Left Atrial Appendage without an implant, reducing the risk of stroke. Append Medical completed its first pre-clinical chronic procedure and is preparing for the first human trials. The company received validation for its approach from IMMR, a Paris-based company that helps conduct pre-clinical studies.","partners":["MEDX Xelerator","Boston Scientific","MEDX Ventures","Sheba Medical Center","IMMR"],"customers":null,"investors":null,"confidence":8,"key_topics":["Append Medical","The Appligator","Atrial Fibrillation","Stroke","Pre-clinical trials"],"date_of_event":null,"valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Partners","Investment"],"acquisition_amount":null,"structuredIssuesShow":"#Partners  #Investment","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"hYeGH0FehByXlqUdgCMANoInKMDGfgRpZ8OcV8t23NZTxc2DqnyVYq","news_summary":"https://www.jpost.com/health-science/israeli-company-soon-to-begin-trial-on-stroke-risk-reduction-device-649063","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"bbaf24bd-08d4-40ad-a350-784fd9891d78","date":"Jun 26, 2020","link":"https://www.jpost.com/opinion/hillels-tech-corner-append-medical-takes-the-unknown-out-of-strokes-632840","source":"www.jpost.com","visible":1,"analysis":{"tags":"medical device","company":"Append Medical","layoffs":null,"summary":"Append Medical, a medical device company, has developed a minimally invasive device called the Appligator™ to reduce stroke risk in patients with atrial fibrillation. The device aims to close the left atrial appendage (LAA), which is a breeding ground for blood clots that can cause strokes. The LAA closure market is projected to reach $958 million by 2025. Append Medical has received funding from MEDX Xelerator, with investments from Boston Scientific, MEDX Ventures, Intellectual Ventures, and the companys founder and CEO, Zachi Berger. The company recently conducted successful clinical trials for its device, and it is supported by a strong scientific advisory board. Despite being a relatively small company, Append Medicals technology shows promise in addressing a significant global health risk.","partners":null,"customers":null,"investors":["Boston Scientific","MEDX Ventures","Intellectual Ventures","Zachi Berger"],"confidence":8,"key_topics":["strokes","atrial fibrillation","minimally invasive medical device","LAA closure","clinical trials"],"date_of_event":null,"valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Customers"],"acquisition_amount":null,"structuredIssuesShow":"#Customers","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"qbQhlGDCHhUDkRPMThzMoDv9CBrz0wdAksbr6uEVNqxWxiGbfOCvjc","news_summary":"https://www.jpost.com/opinion/hillels-tech-corner-append-medical-takes-the-unknown-out-of-strokes-632840","analysisStructuredIssuesDisplay":"block","analysisImpactOnCompanyDisplay":"block"},{"id":"cbb20aa4-c334-46fa-8383-1b84e7acf896","date":"Feb 24, 2020","link":"https://cardiacrhythmnews.com/append-medical-share-clinical-proof-of-concept-results-for-internal-sealing-of-laa/","source":"cardiacrhythmnews.com","visible":1,"analysis":{"tags":"medical device","company":"Append Medical","layoffs":null,"summary":"Append Medical and Sheba Medical Center have announced clinical proof-of-concept data for Appends Appligator LAA closure device. 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In the EU, MEDX Xelerator will collaborate with Health Hub Vienna (HHV), while in the US, it will collaborate with Parvizi Surgical Innovation (PSI). MEDX Xelerator has also launched collaboration with the University of Navarra (UN) in Spain. Through these collaborations, MEDX Xelerator aims to facilitate exchange in fields essential to innovation infrastructure and leverage their networks of strategic partners, hospitals, and universities. The collaborations are part of MEDX Xelerators proactive strategy to address significant unmet medical needs.","partners":["Health Hub Vienna (HHV)","Parvizi Surgical Innovation (PSI)","University of Navarra (UN)"],"customers":null,"investors":null,"confidence":8,"key_topics":["medical technologies","collaboration","innovation hubs","incubator","medical devices"],"date_of_event":"October 14, 2018","valuation_amount":null,"impact_on_company":"growth-positive","investment_amount":null,"structured_issues":["Partners"],"acquisition_amount":null,"structuredIssuesShow":"#Partners","entityGrowthIconPath":"url(/assets/circle-green.svg);"},"sentiment":"growth-positive","analysisId":"pTTPcyIwZyMrnpYjX3OQg68vtf6vWNxdrNkZAORJ8JLJsByMfUcMWm","news_summary":"MEDX Xelerator broadens international 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