Vibrant Gastro Overview
Vibrant Gastro is the developer of the Synchronized Activation Method, a groundbreaking drug-free technology system that uses gentle vibrations to stimulate the colon mechanically. The preprogrammed timing of the mechanical stimulation is designed to improve natural colonic motility by leveraging the colon’s biological clock. The company’s technology system allows for future development of data-driven personalized treatments and additional indications leveraging the gut-brain connection via the enteric nervous system pathway. Vibrant Gastro’s first indication is for treating adults with chronic idiopathic constipation who have not experienced relief of their symptoms after using laxative therapies at the recommended dosage for at least one month.
Cumulative Funding Raised Over Time ($)
Latest News
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How Vibrant Gastro's vibrating pill treats chronic constipation without drugs
Vibrant Gastro has received FDA marketing authorization for its vibrating, drug-free capsule for treating chronic constipation. The capsule, which is activated in an accompanying pod, works by mechanically stimulating the colon and resynchronizing the biological clock to improve bowel movements. The device will be available in select U.S. states early next year and will expand nationally throughout 2023. Clinical trials showed that patients using the Vibrant capsule had at least one additional bowel movement per week compared to the control group. Vibrant Gastro aims to provide a drug-free treatment option for chronic constipation patients and plans to seek an expansion of indications in the future.
Customers
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Vibrant's Novel Drug-Free Treatment Demonstrates Positive Efficacy and Safety Results in Adults with Chronic Idiopathic Constipation in Pivotal Phase 3 Study
Vibrant Gastro presented positive Phase 3 data for its drug-free treatment for chronic idiopathic constipation (CIC) at the 2022 Digestive Disease Week Conference. The data showed significant improvement in bowel movement frequency, constipation symptoms, and quality of life in adults with CIC. The company has submitted the Phase 3 data to the U.S. Food and Drug Administration for clearance. The trial involved 312 CIC patients at over 90 clinical centers across the U.S. Vibrants drug-free mechanism of action is based on resynchronizing the biological clock through mechanical stimulation of the colon. The company aims to provide a cost-effective solution for chronic constipation and expand treatment options for healthcare providers.
Customers
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Constipation treatment Vibrant raises $7.5 million led by Unorthodox Ventures
Vibrant, a developer of gastrointestinal treatments, has announced the first closing of a $7.5 million Series E funding round led by Unorthodox Ventures. Vibrant has developed a non-drug treatment for chronic constipation that uses a vibrating capsule to stimulate bowel movements. The treatment is currently in its third round of trials with the FDA. The funding will support Vibrants expected rollout and the company is actively engaging with physicians and insurers. Unorthodox Ventures Founding Contrarian, Carey Smith, will join Vibrants Board of Directors. Vibrant is aiming to provide a real solution for the millions of Americans suffering from chronic constipation.
Investment
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Swallowable Vibrating Pill Shakes Faecis to Relieve Constipation
Israeli company Vibrant has developed a drug-free pill called the Vibrant capsule, which is swallowed like a typical pill and is programmed to vibrate in order to stimulate bowel movements. The capsule has been evaluated for effectiveness on patients with Chronic Idiopathic Constipation and Irritable Bowel Syndrome with Constipation, showing positive results. The capsule is able to shake up the walls of the large intestine, freeing up tough buildup. The article highlights the benefits of the Vibrant capsule as a medication-free solution for constipation.
Customers
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Drug-Free Constipation Cure: A Vibrating Pill Bottom Line Inc
Israeli company Vibrant has developed a vibrating capsule to provide relief for chronic constipation. The capsule, which is swallowed and programmed to vibrate in the large intestine, stimulates natural peristaltic activity and induces bowel movements. In early clinical trials, the Vibrant capsule doubled the number of bowel movements and achieved effective relief in 90% of patients within eight weeks. The capsule is about the size of a fish oil pill and has no side effects. Vibrant plans to conduct larger trials in 10 to 12 research centers starting in early 2019, with the goal of obtaining FDA approval and making the capsule available in about three years.
Customers
| Sector | Health Tech & Life Sciences |
Funding
| Total funding | $7.5M |
| Last funding | $7.5M |
| Stage | E |
| Rounds | 3 |
| Investors | 4 |
Team Members
6
Employees: 11-50
Web & Social Links
| Website | vibrantgastro.com |
| Careers | Careers page |
Locations
Yokne'am Illit, Israel
Photos & Videos
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