CultivO2 offers an innovative bio convergence platform for the autonomic culture of animal tissue utilizing photosynthetic microalgae, while reducing the amounts of bioreactor-based cell propagation and replacing bioreactors entirely in the differentiation, scaffolding and hypertrophy processes. Thus, it enables cost reduction and scalability of cultured meat production. The live oxygen-producing biomaterial in the system continuously excrete oxygen, growth factors and glucose to the environment surrounding the animal tissue cells, and consumes toxic by-products (e.g. ammonia, lactate), thereby supporting animal cells’ production of animal-based protein for the food industry. Overall, a “symbiotic recycling system” is generated in a way that can eliminate the requirement for a bioreactor while utilizing minimal amounts of media. The platform can support applications such as low-cost cultured-meat production, advanced tissue-culture methods, and algae-based nutritional platform.