SpliSense
RNA-based Treatment for Genetic Diseases
Startup B Health Tech & Life Sciences Est. 2016
Total Raised
$41.5M
B
Last Round
$12M
4 rounds
Investors
6
6 public
Team
3
11-50 employees
Confidence
89/100
News
6
articles
Patents
1
About
SpliSense is a clinical stage company developing transformative RNA-based treatments for unmet needs relating to diverse pulmonary diseases. Its treatment is based on clinically validated Antisense Oligonucleotide (ASO) technology, delivered non-invasively by inhalation to the lungs. The company is focused on a variety of innovative therapies, in different development stages from discovery to IND. Using an innovative approach, SpliSense aims to target the root cause of the disease, to overcome specific genetic mutations and modulate proteins expression and function. The company recieved FDA approval for its lead ASO product, SPL84, for the treatment of patients with cystic fibrosis.
Classification
Sector
Health Tech & Life SciencesPharma & Medical BiotechnologyDrugs Discovery & Development
Core Technology
BiologicalsGenes
Target Customer
Healthcare & Life SciencesLife SciencesPharmaceuticalsBiotechnology
Business Model
B2B
Tags
medical-technologiespharma-companiespharmaceuticalsbiotechnologydrug-developmenttreatmentsgenetics
Funding & Events
Nov 2018
A Round $1M
Integra Holdings
Mar 2021
B Round $28.5M
OrbiMed, Cystic Fibrosis Foundation, Biotel, Integra Holdings, Israel Biotech Fund
Feb 2020
Seed Undisclosed
Israel Biotech Fund
Apr 2024
Undisclosed Round $12M
Cystic Fibrosis Foundation (Lead), Integra Holdings, OrbiMed
News (6)
Sep 3, 2025 · www.prnewswire.com
growth-positive
/PRNewswire/ -- SpliSense, a clinical-stage biotechnology company developing transformative RNA-based therapies for pulmonary diseases, today announced...
Product StageFDA approved/pending approval
May 28, 2024 · www.prnewswire.com
growth-positive
SpliSense Receives FDA Fast Track Designation for SPL84 for the Treatment of Cystic Fibrosis
Jan 4, 2022 · www.prnewswire.com
Growth-Positive
SpliSense Announces FDA and EMA Grant Orphan Drug Designation to SPL84-23-1 for the Treatment of Cystic Fibrosis
CustomersPartners
Jan 4, 2022 · www.jpost.com
growth-positive
Israeli firm SpliSense moves to clinical trials for cystic fibrosis treatment
Investment
Sep 13, 2021 · www.israel21c.org
growth-positive
Inhaled drug could treat rare cystic fibrosis mutations
Customers
May 19, 2021 · cysticfibrosisnewstoday.com
growth-positive
SpliSense Raises $28.5M to Advance Treatments for Rare CF Mutations
Investment
Details
Product Stage
Clinical Trial
Employees
11-50
Exact Count
17
District
Jerusalem District
Founded
2016
Registrar
515535730
Crunchbase
splisense
Locations
Kalman Ya'akov Man St, Jerusalem, Israel
Links
Website
LinkedIn
Careers
Admin
Last Update
Oct 29, 2024
Verified by
Jenny Sotnik-Talisman
Missing
video or image, markets, not claimed
Team (3)
Gili Hart
Acting CEO
Efrat Ozeri-Galai
VP R&D
Yifat Oren
Head of Research
Internal
Created by
Jenny Sotnik-Talisman (genys30@yahoo.com)
Created
2017-09-25T00:00:00.000Z
Last editor
Yanina Wainscheinker (yanina.wainscheinker@sncentral.org)