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ST Innovative Diagnostics

Monitoring Malignancies trough a Simple Blood Test
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1 article
May 18, 2024 · journals.plos.org
Presence and activity of Fibrinogen like protein 2 in platelets
The article discusses a study on the presence and activity of Fibrinogen-like protein 2 (FGL2) in platelets. FGL2 is known for its role in tumor development and metastasis, and the study aimed to determine its presence in blood platelets. The research found that FGL2 is indeed present in platelets and exhibits prothrombinase-like activity, which is significant in the context of blood coagulation and cancer biology. The study also demonstrated that upon activation, platelets secrete active FGL2, suggesting a potential mechanism for its involvement in malignancies. This research provides new insights into the role of platelets in cancer and coagulation processes.